Hi,
is it possible to make physX rigidbody react with cloth sim ?
Not directly, no.
If you don't need 2-way interaction, you can do your PhysX sim...set Mesh to Trimesh (and not 'render only'), and then feed the PhysX sim into another tyFlow object within a collision operator. This will only work properly if the topology of the PhysX flow doesn't change over time (ie, particle count stays the same).